Fallout 76

Set in Appalachia 25 years after the Great War, you play as a dweller recently liberated from Vault 76.  As you attempt to make a new life on the outside you cross paths with different factions of survivors each with conflicting ideas on how to revitalize or conquer Appalachia, which is now home to all manner of enemies, be they human raiders, super mutants, robots or assorted monsters.